Diabetes successfully treated ultrasound in preclinical research consists such an amazing noninvasive technique which is a future blessing for people with diabetes. No matter whether researches, observation, hypothesis, or research trials makes life easy for human bieng.
Diabetes is such a chronic disease that may cause many complications that are accompanied by the treatment of daily basis dosage or insulin injections; as we are in the era of radiation, we are in the storm of rays. Sound waves: Some are hearing(audible), and some are not. All have different frequencies. It is a game of frequency changers. As we know, energy never dies; atoms are not created nor destroyed. They remain in their surroundings or act in their actions.
Ultrasound frequency’s properties:
- The human hearing range is 20 Hz (cycles per second) to 20 kHz (20,000 Hz). Below 20 Hz are infrasonic sound waves, and above 20 kHz are ultrasonic sound waves.
- Ultrasonography uses ultrasonic transducers that produce sound waves above human hearing, typically in the megahertz (MHz) range from 1-20 MHz. Higher frequencies provide better resolution but less penetration.
- For medical imaging, lower MHz frequencies (3.5-5 MHz) are used to image deeper body structures like abdominal organs, fetuses, etc. The lower frequency allows the waves to penetrate deeper before attenuating.
- Higher frequencies (7-15 MHz) are used for more superficial structures like breasts, testes, thyroids, etc. The finer resolution is more important than depth in these areas.
Additionally, focused ultrasonic sound waves provide targeted therapy for treating conditions including kidney stones, gallstones, prostate tumors and insulin resistance in diabetes by mechanisms of stone break up, cancerous tissue ablation and improved insulin absorption respectively.
This research may impact the ultrasonography diagnostic field in the future…
Preclinical study for diabetes through ultrasound:
A preclinical study for diabetes proves that the 1-3 Megahertz frequency of ultrasound rays is enough to stimulate the nerve ending, which sends signals toward the brain message of hyperglycemia; in response, blood-release insulin controls excess sugar and resulting hypoglycemia.
In the journal Nature Biomedical Engineering, a team led by GE Research, including investigators from the Yale School of Medicine, UCLA, and the Feinstein Institutes for Medical Research on treatment of diabetes thrrough ultasound. This process called Peripheral focused ultasound stimulation(pFUS).It involves stimulation of any specific nerve endings; technique through ultrasound that focuses on nerve endings that stimulate insulin release through ultrasound. Porta hepatis, the gate of the liver, consists of the hepatoportal nerve plexus; this region connects the brain and gives information about sugar and other nutrient statuses to the brain; in response, the brain’s action depends on the body’s requirements.
The limitations here are that this is quite a small region; it is challenging to stimulate the specific nerve ending through ultrasound waves. One another important consideration is the consequences of the surrounding nerve stimulation. Either it has good effects or bad. A vast area of research here to do is more effective and useful.
This research has been carried out on three different groups of animals and has had successful results in the secretion of insulin hormones.
This marvelous research study may reduce not only the complications of diabetes chronic diseases but also the painful way of daily dosing or injecting may be reduced. The greater achievement is that diabetic patients may conveniently use this non-invasive way of treatment easily at home.
Evidence to support the preclinical trials to treat diabetes successfully through ultrasound:
Different studies proved that sound waves can stimulate the other parts of the brain at different frequencies1. Research shows a 6 Hz beat stimulates all brain areas within 10 minutes.
For pancreatic islet cells of Langerhans, nerve signal stimulations need a specific frequency to stimulate the insulin hormone. It may cause decrease glycemic index.
One latest reserch publish online 2022 nov 25, also revealed that diabetic foot ulcer has successfuuly treated with low intensity diagnostic ultrasound wit microbubbles. researches carried 20 minutes treatment for seven days completely healed the diabetic foot ulcer2.
This shows that how Diabetes successfully treated ultrasound in preclinical studies become an excellent and bright shine for diabetic treatment and brings glitters and conviency for chronic diabetic patient.
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